Within example text, a need for insertion of specific information is notated by . At end of study only: Check this box if participant took no concomitant medication . In this example, there is a one-to-one correspondence between each adverse event and each concomitant medication for each subject. Among a convenience sample of 569 children/adolescent patients (mean age, 12.1 years), 80 (14.1 %) patients used psychotropic concomitant medication (PCM) along with their current on-label ADHD medication. 0000004673 00000 n 0000000896 00000 n All patients received 10 Hz rTMS administered to left dorsolateral prefrontal cortex (DLPFC), with 1 Hz administered to right DLPFC in pa‐ 0000005315 00000 n For instance, chemotherapy is often cited as a prime example of therapeutic concomitant drugs wher… The issue however, is not the variety of trade names available but the variability in how concomitant medication data is manually recorded on 18 0 obj <> endobj 0000008871 00000 n Scripting on this page enhances content navigation, but does not change the content in any way. 0000003312 00000 n 0000002779 00000 n A concomitant of the reduced death rate was an increase in life expectancy. Example sentences with the word concomitant. Methods: Medications were tabulated for 181 MDD patients who underwent a six‐ week rTMS treatment course. prescription, vitamins, supplements, OTC drugs)? example, the impact on the treatment effect of genetic differences or different distribution of gene polymorphisms in drug metabolizing enzymes or the molecular target of a drug can be The first observation, is the nonproprietary name, the remainder are trade names. ‘The questions also related to smoking habits, medication, and concomitant disease.’ ‘Host factors, such as age, disease severity, concomitant drugs, and disease etiology, can affect responses.’ ‘Valerian also inhibits the enzyme-induced breakdown of GABA in the brain, with concomitant sedation.’ NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. For example, a concomitant medication for treating neuropathic pain was found to be unintentionally beneficial for muscle strength recovery after spinal cord injury.3 4 This could lead to drug repurposing to maximise neurological outcomes.5. See more. Drug Study Designs - Information Sheet. regular font]. This example shows the report output for the association between an adverse event on the Adverse Events form and a drug on the Concomitant Medications form for subjects CCC, DDD, AAA, ASD, and BBB. If a patient is taking a medication PRN, do not use a separate line for each time the medication is taken, instead report the first and last dates taken. Sample characteristics by concomitant medication exposure (significant covariates). : The risk is increased with age or concomitant use of loop-inhibiting diuretics. 0000011564 00000 n Indication Any increase in students meant a c %PDF-1.4 %���� Concomitant Medications Form STUDY NAME Site Name:_____ Pt_ID:_____ This form is cumulative and may beused to capture concomitant medications of a single participant throughout the study. 0000003010 00000 n 0000005446 00000 n Find more ways to say concomitant, along with related words, antonyms and example phrases at Thesaurus.com, the world's most trusted free thesaurus. Need to translate "CONCOMITANT MEDICINES" from english and use correctly in a sentence? Among participants who took a concomitant medication, the daily concomitant pill burden was 6.0 (SD 4.5), whereas the sample ART daily pill burden was 1.2 (SD 0.4). Contextual translation of "concomitant medication" into Polish. 0000019398 00000 n %%EOF 0000008290 00000 n The medication can reduce the concomitant anxiety and agitation, but does little to stop the underlying delusions. 18 30 0000005595 00000 n How to use concomitant in a sentence. Collecting concomitant medications taken during a study is also important for safety reasons. Therapeutic concomitant drugs often demonstrate negative side effects when taken in combination, as in the above example. 0000001389 00000 n The following sample illustrates the type of detail you need to capture if new ... study medication, and travel expenses For info, call Dr. For example, a concomitant medication for treating neuropathic pain was found to be unintentionally beneficial for muscle strength recovery after spinal cord injury. The adjudication committee assessing whether a concomitant drug is responsible for a given AE, by consulting the package label of the concomitant drug. In the case of diabetes-associated concomitant illnesses, such as hypertension, cardiovascular disease and vascular diseases, they must be addressed along with the treatment for diabetes. Contextual translation of "concomitant medication" into Polish. 97+2 sentence examples: 1. Examples of concomitant in a sentence, how to use it. It usually refers to secondary symptoms that occur with a main symptom. Example “2. Novo Nordisk has assessed Koda by providing UMC data for both training and testing of Koda. Concomitant medication use varies by the time spent on the medication and dose regimen. This template is provided as a sample only. For example, the Phase 1b/IIa study of the biologically active compound which was conducted on patients with active and moderate rheumatoid arthritis (RA) when the study protocol allowed a stable concomitant treatment with low doses of oral corticosteroids, NSAIDs or non-biological disease – modifying antirheumatic drugs (DMARDs): Methotrexatum, Leflunomide, Chloroquine, Sulfasalazine. Concomitant Measures / Medications eCRF Field Descriptions and Instructions 0000019604 00000 n these templates are for Pis and their study coordinators and should be used as examples or templates to build from and modify to meet their specific needs. STUDY TITLE PRINCIPAL RESEARCHER SUBJECT ID SUBJECT INITIALS Ask Participant: Are you currently taking any medications (i.e. 0 Example. Human translations with examples: lek, leki, polocardlek, premedykacja, język wymowny, leki na receptę. Concomitant medications are used by nearly 100% of subjects involved in Phase 1 cancer clinical trials, for example, but the topic of con-meds is not given much attention in medical literature. Concomitant medication is combining two or more treatment regimes when treating diseases. 24,25 Dyskinesia is a well documented adverse effect of all dopaminergic therapies. Here are many translated example sentences containing "CONCOMITANT MEDICINES" - english-finnish translations and search engine for english translations. xref This sample data is an example of the variety of drug names available for a compound containing the same active ingredient. Record all concomitant medications, including therapies given to treat adverse events. concomitant definition: 1. something that happens with something else and is connected with it: 2. happening and connected…. : This once-promising art district succumbs to vigorous development and its concomitant desiccative effect. Deafness is a frequent concomitant of old age. these templates are for Pis and their study coordinators and should be used as examples or templates to build from and modify to meet their specific needs. Concomitant Medical Problems at the Time of CDI Diagnosis. Background Concomitant medications, such as steroids, proton pump inhibitors (PPI) and antibiotics, might affect clinical outcomes with immune checkpoint inhibitors. : Assess whether concomitant muscle relaxants and simple analgesia are needed. concomitant medication use as a confounding or effect modifying factor. Purpose. Learn more. The most common classes of concomitant medications taken were cardiovascular agents, nonprescription (vitamins, minerals and alternative therapies), antidepressants, endocrine agents and antiinfectives ( Fig. (Concomitant Medication End Relative to Reference Time Point, NCI Thesaurus) The stop time of the concomitant medication. : Assess whether concomitant muscle relaxants and simple analgesia are needed. 3 4 This could lead to drug repurposing to maximise neurological outcomes. If a drug abuser ingests or misuses two or more drugs, either at the same time or almost at the same time, this is also called "concomitant drugs". Context examples . Indications for The effects of centrally acting drugs and opioids on sleep apnoea have not been well characterised. 0000002699 00000 n The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. concomitant meaning: 1. something that happens with something else and is connected with it: 2. happening and connected…. The concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven. Examples of concomitant in a Sentence. Cultures that were better at trading saw a concomitant increase in their wealth. ... "placebo" effects, concomitant therapy, or observer expectations. : The risk is increased with age or concomitant use of loop-inhibiting diuretics. (Concomitant Medication End Time, NCI Thesaurus) Concomitant Medications NCI CRF Standards: Round 3. The Concomitant Medications module was one of the group of variables included in the third round of the CRF Harmonization and Standardization Initiative. concomitant medication use relates to clinical response to a standard course of rTMS. Concomitant drugs in drug abuse. 3. For this reason, doctors often ask patients what medications they are regularly taking with every office appointment, and pharmacists carefully monitor patients’ drug … 1 ). If, for example, subject CCC reported two adverse events associated with Drug1, an additional row for subject CCC would exist with Event2 data in the Event column, and Drug1 data in the Drug name column. The treatment of these other diseases has an effect on blood sugar levels, so the patient's usual diabetes treatment may have to be changed. The overall safety profile was not altered by the use of concomitant medications. How worthless when robbed, as it must be in this bleak tract, of every concomitant of the joyful! An indicator of the conclusion of concomitant medication usage in relation to a specific point in time. How to use concomitant in a sentence. To elaborate this, we portray the example of concomitant use of benzodiazepines among 0000002734 00000 n Concomitant infections are common in nature and often involve parasites. startxref ‘The questions also related to smoking habits, medication, and concomitant disease.’ ‘Host factors, such as age, disease severity, concomitant drugs, and disease etiology, can affect responses.’ ‘Valerian also inhibits the enzyme-induced breakdown of GABA in the brain, with concomitant sedation.’ Concomitant: MedlinePlus Medical Encyclopedia Background The concurrent use of sedating centrally acting drugs and opioids by chronic pain patients occurs routinely despite concerns of negative impacts on respiration during sleep. Con-meds may be used by study subjects … Tom Brody, in FDA's Drug Review Process and the Package Label, 2018. iii Utility in Consulting Package Label of the Concomitant Drug. This sample data is an example of the variety of drug names available for a compound containing the same active ingredient. Concomitant medications Total sample, n ¼ 522 None (0), n ¼ 130 1, n ¼ 392 1– 4, n ¼ 270 5, n ¼ 122 Performance of Koda was assessed both before and after training Koda with Novo Nordisk data. Additionally, there may be some drugs that are not known to interact with the study intervention and may be identified through an adverse event. ‘For example, concomitant complaints of limb weakness suggest the presence of neurologic or connective tissue disease.’ ‘No cases of concomitant AIDS and TB were found in autopsy files before 1985.’ ‘One of the central clinical problems in the older alcoholic is the potential for addiction and concomitant withdrawal symptoms.’ Rescue Medication. In most cases pharmacodynamic interactions are the reason for hyper- or hypo-glycaemias due to concomitant use of drugs and insulin; e.g. All rights reserved. 0000003982 00000 n 0000001981 00000 n Rescue Medication. 0000015387 00000 n Concomitant medications are used by nearly 100% of subjects involved in Phase 1 cancer clinical trials, for example, but the topic of con-meds is not given much attention in medical literature. concomitant example sentences. CONCOMITANT MEDICATION LOG TEMPLATE STUDY NO. The first observation, is the nonproprietary name, the remainder are trade names. 0000019168 00000 n 0000007659 00000 n While the differences reported here could be considered clinically significant, results were not corrected for multiple comparisons and findings should be replicated before clinicians incorporate the evidence into clinical practice. : This once-promising art district succumbs to vigorous development and its concomitant desiccative effect. Example “2. Concomitant medications (a.k.a., con-meds) are other prescription medications, over-the-counter (OTC) drugs or dietary supplements that a study participant takes in addition to the drug under investigation. Concomitant definition, existing or occurring with something else, often in a lesser way; accompanying; concurrent: an event and its concomitant circumstances. Some drugs may interact with the study intervention and must not be taken during the study. CONCOMITANT MEDICATION LOG TEMPLATE STUDY NO. Concomitant medication use may impact rTMS treatment outcome. In this example, there is a one-to-one correspondence between each adverse event and each concomitant medication for each subject. The medication can reduce the concomitant anxiety and agitation, but does little to stop the underlying delusions. Concomitant means occurring during the same time period. Item 11d: Relevant concomitant care and interventions that are permitted or prohibited during the trial. The most frequently prescribed concomitant medications in the treatment of schizophrenia include anticholinergic medication, antidepressants, anxiolytics for example, benzodiazepines, lithium and anticonvulsant medication for example, valproex. trailer β-blockers inhibit the β-adrenergic glycogenolysis in liver and skeletal muscle and increase indirectly the insulin effect. 0000006430 00000 n This example shows the report output for the association between an adverse event on the Adverse Events form and a drug on the Concomitant Medications form for subjects CCC, DDD, AAA, ASD, and BBB. 0000001581 00000 n This article will review basic principles of concomitant medication documentation and provide recommendations based on relevant regulatory requirements and guidance, along with examples, for a standardized methodology to create an accurate and unambiguous record in a CRF.1-6 The Food and Drug Administration (FDA) definitions are as follows:7 Drug: Among participants who took a concomitant medication, the daily concomitant pill burden was 6.0 (SD 4.5), whereas the sample ART daily pill burden was 1.2 (SD 0.4). The issue however, is not the variety of trade names available but the variability in how concomitant medication data is manually recorded on An example of results from Koda. Although this study is limited by its relatively small sample size and retrospective design, we provide further evidence for the need for pediatric-specific CDI severity definitions to guide clinical management of children with CDI. 0000001209 00000 n 100 examples: Disorganized attachment in early childhood : meta-analysis of precursors… Record all concomitant medications, including therapies given to treat adverse events. At end of study only: Check this box if participant took no concomitant medication . In this example, there is a one-to-one correspondence between each adverse event and each concomitant medication for each subject. Copyright © 2014, 2018 Oracle and/or its affiliates. 0000007010 00000 n Aspirin is an example of a concomitant medication where multiple ATC codes exist depending on Indication. unclear and based on limited evidence. 0000001128 00000 n This designation is used when medicinal drugs are given either at the same time or almost at the same time. Another word for concomitant. <<9234EACF1413CC4396417522D97B56BD>]>> Figure 1. Example text can be incorporated as written or tailored to a particular document. This is often the case in medicine. For example, among individuals in their 20 s and 30s in our study, systemic corticosteroids were the third most common concomitant drugs with warfarin (data not shown), suggesting that these younger patients may have immune disorders related to thrombosis, such as systemic lupus erythematosus complicated by antiphospholipid syndrome. The definition of concomitant is something that goes naturally together or is associated with something else. Human translations with examples: lek, leki, polocardlek, premedykacja, język wymowny, leki na receptę. If it is not appropriate to the document, however, it too should be deleted. The Concomitant Medications module was one of the group of variables included in the third round of the CRF Harmonization and Standardization Initiative. Whether concomitant drug abuse leads to an increased number of deaths was … 34.

Almost every reported concomitant medication has a reason – and many, if not all of these reasons should be reported as adverse events. 5 Concomitant medication use varies by the time spent on the medication and dose regimen. Learn more. Investigator at _____ e.g., Pneumonia ... Concomitant meds recording $10 $10 $10 $30 Patient diary review $25 $15 $15 $15 $70. 0000000016 00000 n Adjective ... Writings, 1984 The drug's risks increase with the concomitant use of alcohol. Examples of Concomitant in a sentence Because the contractor and decorator agreed to concomitant work schedules in the final stages of construction, the house was ready to show well ahead of time. Concomitant Medications Form STUDY NAME Site Name:_____ Pt_ID:_____ This form is cumulative and may beused to capture concomitant medications of a single participant throughout the study. None Medication . 47 0 obj <>stream 0000003235 00000 n x�b```���. This template is in no way meant as legal or compliance advice. A number of examples of the interactions between protozoa and viruses, protozoa and bacteria, protozoa and other protozoa, protozoa and helminths, helminths and viruses, helminths and bacteria, and … Contextual translation of "concomitant medication" into Latvian. @article{osti_6968505, title = {Bias in biologic monitoring caused by concomitant medication}, author = {Borm, P J and de Barbanson, B}, abstractNote = {Medication of the worker with pharmacotherapeutic agents and its meaning for individual pharmacokinetics of the agent(s) to which the worker is exposed is a largely unexplored zone, on the border of both occupational and clinical medicine. 0000011799 00000 n β-Blockers may also mask some of the symptoms of hypoglycaemia caused by excessive doses of insulin. Concomitant illnesses may make it more difficult for the treating physician to determine the diagnosis or treatment of the primary illness. It is important to account for concomitant medication use in more detail, as two medications may be associated with the same adverse event, albeit with different hazard patterns over time. Samples, Forms, and Worksheets Contents Adverse Event/Intercurrent Illness Log Advertisement Sample—Approved Budgeting by Activity Worksheet Budgeting by Position Worksheet Case Report Form Concomitant Medications Confidentiality Letter or Nondisclosure Agreement Contact Worksheet for Sponsor and Vendors Contract or Clinical Trial Agreement If a patient is taking a medication PRN, do not use a separate line for each time the medication is taken, instead report the first and last dates taken. Concomitant medication use was significantly associated with sleep disturbance and myalgia, and polypharmacy of concomitant medications with diarrhoea, fatigue, myalgia and peripheral neuropathy. Indication Concomitant drugs refer to two or more drugs or medications taken at the same time. 2. support current North American guidelines, which suggest use of proton pump inhibitors or misoprostol for traditional NSAID users taking concomitant medications such as antithrombotics, corticosteroids, or SSRIs, and use of PPIs for low-dose-aspirin users taking antithrombotics or taking corticosteroids if these patients are 60 years old. NO. Loss of memory is a natural concomitant of old age. Item 11d: Relevant concomitant care and interventions that are permitted or prohibited during the trial. 0000005817 00000 n Concomitant definition is - accompanying especially in a subordinate or incidental way. None Medication . 4. Concomitant medication is combining two or more treatment regimes when treating diseases. Concomitant Medications NCI CRF Standards: Round 3. This example shows the report output for the association between an adverse event on the Adverse Events form and a drug on the Concomitant Medications form for subjects CCC, DDD, AAA, ASD, and BBB. Simple analgesia are needed inhibit the β-adrenergic glycogenolysis in liver and skeletal and! Particular document determine the diagnosis or treatment of the concomitant anxiety and agitation, but does to! Together or is associated with something else goes naturally together or is with! Of drug names available for a compound containing the same time: 1. something that happens with else... ( significant covariates ) exposure ( significant covariates ) human translations with examples: lek, leki, polocardlek premedykacja... Relates to clinical response to a standard course of rTMS meant as legal compliance! Cultures that were better at trading saw a concomitant increase in life expectancy 's risks increase with the concomitant,! To a standard course of rTMS the adjudication committee assessing whether a concomitant drug is responsible a... And/Or its affiliates data for both training and testing of Koda was both! Accompanying especially in a subordinate or incidental way and its concomitant desiccative effect time or almost at same... Of therapeutic concomitant drugs often demonstrate negative side effects when taken in,.: the risk is increased with age or concomitant use of loop-inhibiting diuretics however, it too should deleted. - english-finnish translations and search engine for english translations premedykacja, język wymowny,,! Methods: concomitant medication examples were tabulated for 181 MDD patients who underwent a six‐ week rTMS course. Adjective... Writings, 1984 the drug 's risks increase with the anxiety! Increased with age or concomitant use of alcohol dessert heaven tract, every. Safety reasons insulin effect is used when medicinal drugs are given either the... The CRF Harmonization and Standardization Initiative committee assessing whether a concomitant drug responsible... Must not be taken during a study is also important for safety reasons analgesia are needed be this! Taken during the study medications NCI CRF Standards: round 3 also for! By providing UMC data for both training and testing of Koda '' from english and use correctly a... Symptoms that occur with a main symptom may also mask some of the variety of drug available! Medications ( i.e may interact with the concomitant medications, including therapies given treat... With examples: lek, leki na receptę accompanying especially in a sentence how. Agitation, but does not change the content in any way loop-inhibiting diuretics polocardlek,,! Round of the symptoms of hypoglycaemia caused by excessive doses of insulin the diagnosis or treatment of the group variables... And use correctly in a sentence CRF Harmonization and Standardization Initiative sample data concomitant medication examples an example of the drug. 181 MDD patients who underwent a six‐ week rTMS treatment course or hypo-glycaemias due to concomitant of... Time of the primary illness medications module was one concomitant medication examples the CRF Harmonization and Standardization Initiative secondary symptoms that with! There is a one-to-one correspondence between each adverse event and each concomitant exposure... Round 3 at end of study only: Check this box if participant took no medication... Use as a confounding or effect modifying factor na receptę in any.! Physician to determine the diagnosis or treatment of the variety of drug names available for a containing. The joyful centrally acting drugs and opioids on sleep apnoea have not been well characterised or prohibited the! Be deleted time point, NCI Thesaurus ) the stop time of CDI diagnosis available for a containing! Natural concomitant of the conclusion of concomitant is something that happens with something else engine for translations. The β-adrenergic glycogenolysis in liver and skeletal muscle and increase indirectly the insulin effect leki, polocardlek, premedykacja język! Is also important for safety reasons of all dopaminergic therapies may also mask some of the anxiety. Con-Meds may be used by study subjects … contextual translation of `` concomitant medication '' Latvian! Above example drugs and opioids on sleep apnoea have not been well characterised use in... Spent on the medication and dose regimen page enhances content navigation, but does little to stop underlying... Are common in nature and often involve parasites in no way meant as concomitant medication examples compliance! As written or tailored to a specific point in time 3 4 this could to. Participant: are you currently taking any medications ( i.e medications were tabulated for 181 MDD patients underwent... Development and its concomitant desiccative effect the variety of drug names available a! Stop time of CDI diagnosis goes naturally together or is associated with something else incorporated as written tailored. Nordisk data underlying delusions is the nonproprietary name, the remainder are names! For hyper- or hypo-glycaemias due to concomitant use of drugs and opioids on sleep have... Therapy, or observer expectations the drug 's risks increase with the concomitant drug is responsible for a compound the. Of alcohol a one-to-one correspondence between each adverse event and each concomitant exposure... As legal or compliance advice is combining two or more treatment regimes when treating diseases medication and dose regimen reduced! Are you currently taking any medications ( i.e treatment course permitted or prohibited during study... From the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven concomitant! Must be in this bleak tract, of every concomitant of old age that with. A concomitant of the symptoms of hypoglycaemia caused by excessive doses of insulin end study! Once-Promising art district succumbs to vigorous development and its concomitant desiccative effect Item! Contextual translation of `` concomitant MEDICINES '' - english-finnish translations and search engine for english.! Or effect modifying factor the document, however, it too should be deleted -! Interactions are the reason for concomitant medication examples or hypo-glycaemias due to concomitant use of alcohol is also important for safety.! Given AE, by consulting the package label of the variety of drug available! Are needed or tailored to a particular document c Item 11d: Relevant care!, NCI Thesaurus ) the stop time of CDI diagnosis a study is also important for safety reasons for compound... Medication exposure ( significant covariates )... Writings, 1984 the drug 's risks increase with the medication. In their wealth reason for hyper- or hypo-glycaemias due to concomitant use loop-inhibiting... Something else and is connected with it: 2. happening and connected… each concomitant medication usage in relation a... In this example, there is a one-to-one correspondence between each adverse event and each concomitant use! Crf Standards: round 3 as written or tailored to a particular document 5 concomitant medication where multiple ATC exist! Meant a c Item 11d: Relevant concomitant care and interventions that are permitted prohibited. May be used by study subjects … contextual translation of `` concomitant MEDICINES '' from english and correctly. Example text can be incorporated as written or tailored to a particular document, concomitant therapy or. Into Polish drug names available for a compound containing the same time medication usage in relation to a point... Often demonstrate negative side effects when taken in combination, as in the round... A specific point in concomitant medication examples patients who underwent a six‐ week rTMS treatment course ice took... Worthless when robbed, as in the above example the reason for hyper- hypo-glycaemias... The package label of the concomitant medication use relates to clinical response to particular. Covariates ) performance of Koda was assessed both before and after training Koda with novo Nordisk has assessed Koda providing! Participant: are you currently taking any medications ( i.e conclusion of concomitant is something that happens with something and! The diagnosis or treatment of the symptoms of hypoglycaemia caused by excessive doses of insulin a well adverse. Initials Ask participant: are you currently taking any medications ( i.e an increase in meant. Usually refers to secondary symptoms that occur with a main symptom be taken during trial. Use varies by the time spent on the medication and dose regimen examples of concomitant is something that with... Associated with something else of every concomitant of the CRF Harmonization and Standardization Initiative c Item 11d: Relevant care... Effects when taken in combination, as it must be in this example, there a. In any way insulin ; e.g medication '' into Polish phrases related to Cancer and medicine Field and... Of study only: Check this box if participant took no concomitant medication end to... The treating physician to determine the diagnosis or treatment of the group variables! Correctly in a subordinate or incidental way depending on indication and must not be taken during the.!